I used to get minor neuropathy in my arms and hands, mostly from how I slept. After taking this specific form of B1, I noticed a big improvement. I’m not diabetic, just sharing my experience. It's worth reading up on B vitamins and trying to get them from your diet too. I also take 10000 IU of Vitamin D3 daily with Vitamin K to help move calcium into the bones instead of the bloodstream. This B1 is a form your body can absorb right away, not like regular B1. I take a B complex with methylated B12, which works better than synthetic forms like cyanocobalamin. I also take extra under the tongue. B vitamins might make your urine smell, which is totally normal. A nurse once mentioned that to me. Hope this helps someone find what works.